4-氨基-4-(氨基甲基)哌啶-1-羧酸叔丁酯合成路线 （共 6 条）
反应条件
water; potassium carbonate in methanol Heating / reflux;
参考文献
Cumbre Inc.
Patent: US2005/277633 A1, 2005 ;
Location in patent: Page/Page column 14 ;
US 20050277633 A1
反应条件
trifluoroacetic anhydride in pyridine; 4-(dicyanomethylene)-2-methyl-6-(4-dimethylaminostyryl)-4H-pyran; Petroleum ether
反应条件
1: pyridine / methanol / 18 h / 0 °C 2: H2 / Raney-Ni / ethanol / 18 h / 20 °C 3: 88 percent / pyridine / 18 h / 0 °C 4: NH3 / methanol / 18 h / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 5 p. 1181 - 1184
反应条件
1: H2 / Raney-Ni / ethanol / 18 h / 20 °C 2: 88 percent / pyridine / 18 h / 0 °C 3: NH3 / methanol / 18 h / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 5 p. 1181 - 1184
反应条件
1: NH3; NH4Cl / methanol / 3 h / Heating 2: pyridine / methanol / 18 h / 0 °C 3: H2 / Raney-Ni / ethanol / 18 h / 20 °C 4: 88 percent / pyridine / 18 h / 0 °C 5: NH3 / methanol / 18 h / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 5 p. 1181 - 1184
反应条件
ammonia in methanol 18 h; Heating;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 17, # 5 p. 1181 - 1184
