1-Boc-4-氨基哌啶合成路线

参考文献

EISAI RandD MANAGEMENT CO., LTD.; YOSHIDA, Ichiro; OKABE, Tadashi; MATSUMOTO, Yasunobu; WATANABE, Nobuhisa; ONIZAWA, Yuji; OHASHI, Yoshiaki; HARADA, Hitoshi
Patent: US2013/65925 A1, 2013 ;
US 20130065925 A1

87120-72-71-Boc-4-氨基哌啶

1228630-89-4叔丁基 4-硝基哌啶-1-羧酸

参考文献

Mullen, Philip; Miel, Hugues; Anthony McKervey
Tetrahedron Letters, 2010 , vol. 51, # 24 p. 3216 - 3217

87120-72-71-Boc-4-氨基哌啶

782446-06-4

参考文献

Foley, Timothy L.; Rai, Ganesha; Yasgar, Adam; Daniel, Thomas; Baker, Heather L.; Attene-Ramos, Matias; Kosa, Nicolas M.; Leister, William; Burkart, Michael D.; Jadhav, Ajit; Simeonov, Anton; Maloney, David J.
Journal of Medicinal Chemistry, 2014 , vol. 57, # 3 p. 1063 - 1078

87120-72-71-Boc-4-氨基哌啶+

120-92-3环戊酮

812690-40-71-Boc-4-环戊基氨基-哌啶

参考文献

PFIZER LIMITED; PFIZER INC.
Patent: WO2004/111003 A1, 2004 ;
Location in patent: Page 63-64 ;
WO 2004/111003 A1

453-72-52-氟-5-甲基磺酰硝基苯+

87120-72-71-Boc-4-氨基哌啶

849035-91-22-甲基-2-丙基4-氨基-4-[4-(甲基磺酰基)-2-硝基苯基]-1-哌啶羧酸酯

参考文献

PFIZER PRODUCTS INC.
Patent: WO2008/84300 A1, 2008 ;
Location in patent: Page/Page column 90; 91 ;
WO 2008/084300 A1

87120-72-71-Boc-4-氨基哌啶+

88-73-3邻氯硝基苯

87120-73-84-(2-硝基苯氨基)哌啶-1-甲酸叔丁酯

参考文献

Obase; Takai; Teranishi; Nakamizo
Journal of Heterocyclic Chemistry, 1983 , vol. 20, # 3 p. 565 - 573

87120-72-71-Boc-4-氨基哌啶

87120-73-84-(2-硝基苯氨基)哌啶-1-甲酸叔丁酯

参考文献

Pryde, David C.; Tran, Thien-Duc; Gardner, Iain; Bright, Helen; Stupple, Paul; Galan, Sebastien; Alsop, Liam; Watson, Lesa; Middleton, Donald S.; Dayal, Satish; Platts, Michelle; Murray, Edward J.; Parkinson, Tanya; Webster, Robert
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 3 p. 827 - 833

87120-72-71-Boc-4-氨基哌啶+

3958-60-92-硝基苄溴

87120-79-44-(2-硝基苄基氨基)哌啶-1-羧酸叔丁酯

参考文献

Gutierrez, Corey; Termin, Andreas; Hadida-Ruah, Sara; Joshi, Pramod; Bergeron, Daniele; Yoo, Sanghee; Binch, Hayley; Come, Jon; Cao, Jingrong; Nanthakumar, Suganthi
Patent: US2008/4261 A1, 2008 ;
Location in patent: Page/Page column 138 ;
US 20080004261 A1

87120-72-71-Boc-4-氨基哌啶+

552-89-6邻硝基苯甲醛

87120-79-44-(2-硝基苄基氨基)哌啶-1-羧酸叔丁酯

参考文献

Obase; Takai; Teranishi; Nakamizo
Journal of Heterocyclic Chemistry, 1983 , vol. 20, # 3 p. 565 - 573

87120-72-71-Boc-4-氨基哌啶

87120-81-84-(2-氧代-2,3-二氢-1H-苯并[d]咪唑-1-基)哌啶-1-羧酸叔丁酯

参考文献

Zou, Benli; Yuan, Qiliang; Ma, Dawei
Organic Letters, 2007 , vol. 9, # 21 p. 4291 - 4294