4-(2-氧代-2,3-二氢-1H-苯并[d]咪唑-1-基)哌啶-1-羧酸叔丁酯合成路线

参考文献

Butler, Christopher R.; Cai, Hui; Edwards, James P.; Grice, Cheryl A.; Gu, Yin; Gustin, Darin J.; Karlsson, Lars; Khatuya, Haripada; Meduna, Steven P.; Pio, Barbara A.; Sehon, Clark A.; Sun, Siquan; Tays, Kevin L.; Thurmond, Robin L.; Wei, Jianmei
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87120-81-84-(2-氧代-2,3-二氢-1H-苯并[d]咪唑-1-基)哌啶-1-羧酸叔丁酯+

74-88-4甲基碘

173843-48-64-(3-甲基-2-氧代-2,3-二氢-苯并咪唑-1-基)-哌啶-1-羧酸叔丁酯

参考文献

Merck and Co., Inc.
Patent: US5760054 A1, 1998 ;
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87120-81-84-(2-氧代-2,3-二氢-1H-苯并[d]咪唑-1-基)哌啶-1-羧酸叔丁酯

20662-53-74-（2-酮酸-1-苯并咪唑）哌啶

参考文献

Synthetic Communications, , vol. 43, # 13 p. 1796 - 1801

24424-99-5二碳酸二叔丁酯+

20662-53-74-（2-酮酸-1-苯并咪唑）哌啶

87120-81-84-(2-氧代-2,3-二氢-1H-苯并[d]咪唑-1-基)哌啶-1-羧酸叔丁酯

参考文献

SCHERING CORPORATION
Patent: WO2003/103669 A1, 2003 ;
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87120-72-71-Boc-4-氨基哌啶

87120-81-84-(2-氧代-2,3-二氢-1H-苯并[d]咪唑-1-基)哌啶-1-羧酸叔丁酯

参考文献

Zou, Benli; Yuan, Qiliang; Ma, Dawei
Organic Letters, 2007 , vol. 9, # 21 p. 4291 - 4294

32315-10-9三光气+

79099-00-64-(2-氨基苯氨基)哌啶-1-甲酸叔丁酯

87120-81-84-(2-氧代-2,3-二氢-1H-苯并[d]咪唑-1-基)哌啶-1-羧酸叔丁酯

参考文献

Rasheed, Mohammed Abdul; Shaik, Nagul Meera; Nirogi, Ramakrishna
Synthetic Communications, 2013 , vol. 43, # 13 p. 1796 - 1801

41840-28-22-Boc-硫代-4,6-二甲基嘧啶+

20662-53-74-（2-酮酸-1-苯并咪唑）哌啶

87120-81-84-(2-氧代-2,3-二氢-1H-苯并[d]咪唑-1-基)哌啶-1-羧酸叔丁酯

参考文献

Obase; Takai; Teranishi; Nakamizo
Journal of Heterocyclic Chemistry, 1983 , vol. 20, # 3 p. 565 - 573

24424-99-5二碳酸二叔丁酯+

497-19-8碳酸钠+

20662-53-74-（2-酮酸-1-苯并咪唑）哌啶

87120-81-84-(2-氧代-2,3-二氢-1H-苯并[d]咪唑-1-基)哌啶-1-羧酸叔丁酯

参考文献

Merck and Co., Inc.
Patent: US5760054 A1, 1998 ;
US 5760054 A

959700-72-2+

32315-10-9三光气

参考文献

Kuethe, Jeffrey T.; Varon, Jack; Childers, Karla G.
Tetrahedron, 2007 , vol. 63, # 46 p. 11489 - 11502

87120-72-71-Boc-4-氨基哌啶

87120-81-84-(2-氧代-2,3-二氢-1H-苯并[d]咪唑-1-基)哌啶-1-羧酸叔丁酯

参考文献

Pryde, David C.; Tran, Thien-Duc; Gardner, Iain; Bright, Helen; Stupple, Paul; Galan, Sebastien; Alsop, Liam; Watson, Lesa; Middleton, Donald S.; Dayal, Satish; Platts, Michelle; Murray, Edward J.; Parkinson, Tanya; Webster, Robert
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