4-(2-氧代-2,3-二氢-1H-苯并[d]咪唑-1-基)哌啶-1-羧酸叔丁酯合成路线 （共 13 条）
反应条件
1: ammonium formate; palladium hydroxide on carbon / ethanol / 75 °C
2: triethylamine / tetrahydrofuran / 20 °C
View Scheme
参考文献
Pryde, David C.; Tran, Thien-Duc; Gardner, Iain; Bright, Helen; Stupple, Paul; Galan, Sebastien; Alsop, Liam; Watson, Lesa; Middleton, Donald S.; Dayal, Satish; Platts, Michelle; Murray, Edward J.; Parkinson, Tanya; Webster, Robert
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 3 p. 827 - 833
反应条件
1.1: acetic acid / dichloromethane / 0.25 h / 0 °C
1.2: 16 h / 0 - 20 °C
2.1: dichloromethane / 0.5 h / 0 - 20 °C
View Scheme
参考文献
Rasheed, Mohammed Abdul; Shaik, Nagul Meera; Nirogi, Ramakrishna
Synthetic Communications, 2013 , vol. 43, # 13 p. 1796 - 1801
反应条件
1.1: acetic acid / dichloromethane / 0.25 h / 0 °C
1.2: 16 h / 0 - 20 °C
2.1: dichloromethane / 0.5 h / 0 - 20 °C
View Scheme
参考文献
Rasheed, Mohammed Abdul; Shaik, Nagul Meera; Nirogi, Ramakrishna
Synthetic Communications, 2013 , vol. 43, # 13 p. 1796 - 1801
