5-氧代-环己烷-1,3-二羧酸二甲酯合成路线 （共 4 条）
反应条件
diethylamino-sulfur trifluoride in ethanol; dichloromethane T=0 - 25°C; Inert atmosphere;
参考文献
H. LUNDBECK A/S
Patent: US2011/98299 A1, 2011 ;
Location in patent: Page/Page column 41 ;
反应条件
pyridine-SO3 complex; triethylamine in dichloromethane; dimethyl sulfoxide
T=10 - 25°C; Inert atmosphere;
参考文献
H. LUNDBECK A/S
Patent: US2011/98299 A1, 2011 ;
Location in patent: Page/Page column 40 ;
反应条件
potassium carbonate in DMF (N,N-dimethyl-formamide)
T=20°C;
参考文献
TARGACEPT, INC.
Patent: WO2005/37832 A2, 2005 ;
Location in patent: Page/Page column 84 ;
WO 2005/037832 A2
反应条件
1: hydrogen; acetic acid / Rh/Al2O3 / methanol / 0 - 25 °C / 2844.39 Torr
2: triethylamine; pyridine-SO3 complex / dichloromethane; dimethyl sulfoxide / 10 - 25 °C / Inert atmosphere
View Scheme
参考文献
H. LUNDBECK A/S
Patent: US2011/98299 A1, 2011 ;
