potassium carbonate in methanol 1 h; Reflux;

3,4,5,6-tetramethyl-t-Bu-X-Phos; palladium diacetate; potassium carbonate; 2,2,2-trimethylacetic acid in dimethylammonium 2,4-dichlorophenoxyacetate T=110°C; 16 h; Inert atmosphere; regioselective reaction;

potassium carbonate in methanol T=55°C; 2 h; Cooling;