5-溴-2-甲氧基甲苯磺酸苯酯合成路线 （共 6 条）
反应条件
1.1: 91 percent / LDA / heptane; tetrahydrofuran; ethylbenzene / 0.08 h / 0 °C 2.1: 96 percent / potassium carbonate / dimethylsulfoxide / 2 h / 55 °C 3.1: tert-butyllithium / tetrahydrofuran; pentane / 1 h / -78 °C 3.2: 81 percent / trimethyl borate / tetrahydrofuran; pentane / -78 - 20 °C View Scheme
参考文献
Tetrahedron, , vol. 62, # 4 p. 594 - 604
反应条件
lithium diisopropyl amide in tetrahydrofuran; n-heptane; ethylbenzene T=0°C; 0.0833333 h;
参考文献
Fujikawa, Naotaka; Ohta, Takeshi; Yamaguchi, Tomohiro; Fukuda, Tsutomu; Ishibashi, Fumito; Iwao, Masatomo
Tetrahedron, 2006 , vol. 62, # 4 p. 594 - 604
反应条件
N-bromosuccinmide in N,N-dimethyl-formamide
T=20°C; 24 h;
参考文献
Fujikawa, Naotaka; Ohta, Takeshi; Yamaguchi, Tomohiro; Fukuda, Tsutomu; Ishibashi, Fumito; Iwao, Masatomo
Tetrahedron, 2006 , vol. 62, # 4 p. 594 - 604
反应条件
1: zinc(II) chloride / 120 °C / Inert atmosphere
2: hydrogen bromide; dihydrogen peroxide / water / 8 h / 10 °C / Inert atmosphere
View Scheme
参考文献
RHODIA (CHINA) CO., LTD.; RHODIA OPERATIONS; MERCIER, Claude; DE CAMPO, Floryan; RIGHINI, Sebastien
Patent: WO2011/143819 A1, 2011 ;
反应条件
1: 0.75 g / NaOH / H2O; tetrahydrofuran / 5 h / Heating
2: 0.52 g / K2CO3 / dimethylformamide / 12 h / 80 °C
View Scheme
参考文献
Kurono, Nobuhito; Inoue, Tomio; Tokuda, Masao
Tetrahedron, 2005 , vol. 61, # 47 p. 11125 - 11131
反应条件
1: 91 percent / LDA / heptane; tetrahydrofuran; ethylbenzene / 0.08 h / 0 °C
2: 96 percent / potassium carbonate / dimethylsulfoxide / 2 h / 55 °C
View Scheme
参考文献
Fujikawa, Naotaka; Ohta, Takeshi; Yamaguchi, Tomohiro; Fukuda, Tsutomu; Ishibashi, Fumito; Iwao, Masatomo
Tetrahedron, 2006 , vol. 62, # 4 p. 594 - 604
