bromine; acetic acid in dichloromethane 16 h;

potassium fluoride; tris(dibenzylideneacetone)dipalladium(0) chloroform complex; tri-tert-butyl phosphine in tetrahydrofuran; hexane T=25°C; 5 h;

1: With sodium carbonate; bis-triphenylphosphine-palladium(II) chloride in tetrahydrofuran; water T=65°C; 2 h; 2: With N-acetyl-(R)-cysteine in tetrahydrofuran T=65°C; 1 h;