1: 88 percent / HCl / 12 h / 4 °C 2: 24 percent / NaBH4 / ethanol / 16 h / 40 °C 3: 98 percent / 2 N KOH / methanol / 50 °C 4: 67 percent / Na2Cr2O7, conc. H2SO4 / diethyl ether / 2 h / Ambient temperature 5: 55 percent / 2 N NaOH, NaBH4 / ethanol / 16 h / 50 °C / EtOH, Na 6: 98 percent / 20percent diisobutyl aluminium hydride / toluene; hexane / 2 h / -40 °C 7: 99 percent / p-toluenesulfonic acid, molecular sieve 4 Angstroem / diethyl ether; petroleum ether / 1 h / Ambient temperature 8: 80 percent / HCl / diethyl ether View Scheme

1: 24 percent / NaBH4 / ethanol / 16 h / 40 °C 2: 98 percent / 2 N KOH / methanol / 50 °C 3: 67 percent / Na2Cr2O7, conc. H2SO4 / diethyl ether / 2 h / Ambient temperature 4: 55 percent / 2 N NaOH, NaBH4 / ethanol / 16 h / 50 °C / EtOH, Na 5: 98 percent / 20percent diisobutyl aluminium hydride / toluene; hexane / 2 h / -40 °C 6: 99 percent / p-toluenesulfonic acid, molecular sieve 4 Angstroem / diethyl ether; petroleum ether / 1 h / Ambient temperature 7: 80 percent / HCl / diethyl ether View Scheme

1: 77 percent / dimethylsulfoxide / 70 °C 2: 88 percent / HCl / 12 h / 4 °C 3: 24 percent / NaBH4 / ethanol / 16 h / 40 °C 4: 98 percent / 2 N KOH / methanol / 50 °C 5: 67 percent / Na2Cr2O7, conc. H2SO4 / diethyl ether / 2 h / Ambient temperature 6: 55 percent / 2 N NaOH, NaBH4 / ethanol / 16 h / 50 °C / EtOH, Na 7: 98 percent / 20percent diisobutyl aluminium hydride / toluene; hexane / 2 h / -40 °C 8: 99 percent / p-toluenesulfonic acid, molecular sieve 4 Angstroem / diethyl ether; petroleum ether / 1 h / Ambient temperature 9: 80 percent / HCl / diethyl ether View Scheme

1: 94 percent / Na2Cr2O7, conc. H2SO4 / diethyl ether; H2O / 25 °C 2: 88 percent / HCl / 12 h / 4 °C 3: 24 percent / NaBH4 / ethanol / 16 h / 40 °C 4: 98 percent / 2 N KOH / methanol / 50 °C 5: 67 percent / Na2Cr2O7, conc. H2SO4 / diethyl ether / 2 h / Ambient temperature 6: 55 percent / 2 N NaOH, NaBH4 / ethanol / 16 h / 50 °C / EtOH, Na 7: 98 percent / 20percent diisobutyl aluminium hydride / toluene; hexane / 2 h / -40 °C 8: 99 percent / p-toluenesulfonic acid, molecular sieve 4 Angstroem / diethyl ether; petroleum ether / 1 h / Ambient temperature 9: 80 percent / HCl / diethyl ether View Scheme

1: 50 percent / dimethylsulfoxide / 2 h / 70 °C 2: 94 percent / Na2Cr2O7, conc. H2SO4 / diethyl ether; H2O / 25 °C 3: 88 percent / HCl / 12 h / 4 °C 4: 24 percent / NaBH4 / ethanol / 16 h / 40 °C 5: 98 percent / 2 N KOH / methanol / 50 °C 6: 67 percent / Na2Cr2O7, conc. H2SO4 / diethyl ether / 2 h / Ambient temperature 7: 55 percent / 2 N NaOH, NaBH4 / ethanol / 16 h / 50 °C / EtOH, Na 8: 98 percent / 20percent diisobutyl aluminium hydride / toluene; hexane / 2 h / -40 °C 9: 99 percent / p-toluenesulfonic acid, molecular sieve 4 Angstroem / diethyl ether; petroleum ether / 1 h / Ambient temperature 10: 80 percent / HCl / diethyl ether View Scheme

1: 67 percent / Na2Cr2O7, conc. H2SO4 / diethyl ether / 2 h / Ambient temperature 2: 55 percent / 2 N NaOH, NaBH4 / ethanol / 16 h / 50 °C / EtOH, Na 3: 98 percent / 20percent diisobutyl aluminium hydride / toluene; hexane / 2 h / -40 °C 4: 99 percent / p-toluenesulfonic acid, molecular sieve 4 Angstroem / diethyl ether; petroleum ether / 1 h / Ambient temperature 5: 80 percent / HCl / diethyl ether View Scheme

1: 98 percent / 2 N KOH / methanol / 50 °C 2: 67 percent / Na2Cr2O7, conc. H2SO4 / diethyl ether / 2 h / Ambient temperature 3: 55 percent / 2 N NaOH, NaBH4 / ethanol / 16 h / 50 °C / EtOH, Na 4: 98 percent / 20percent diisobutyl aluminium hydride / toluene; hexane / 2 h / -40 °C 5: 99 percent / p-toluenesulfonic acid, molecular sieve 4 Angstroem / diethyl ether; petroleum ether / 1 h / Ambient temperature 6: 80 percent / HCl / diethyl ether View Scheme

1: 99 percent / HCl / diethyl ether / 17 h / -5 °C 2: 80 percent / 0.2 N HCl / diethyl ether / 17 h / Ambient temperature 3: 98 percent / 20percent diisobutyl aluminium hydride / toluene; hexane / 2 h / -40 °C 4: 99 percent / p-toluenesulfonic acid, molecular sieve 4 Angstroem / diethyl ether; petroleum ether / 1 h / Ambient temperature 5: 80 percent / HCl / diethyl ether View Scheme

1: 55 percent / 2 N NaOH, NaBH4 / ethanol / 16 h / 50 °C / EtOH, Na 2: 98 percent / 20percent diisobutyl aluminium hydride / toluene; hexane / 2 h / -40 °C 3: 99 percent / p-toluenesulfonic acid, molecular sieve 4 Angstroem / diethyl ether; petroleum ether / 1 h / Ambient temperature 4: 80 percent / HCl / diethyl ether View Scheme

1: 1) NaH, 2) conc. HBr / 1) DMF, 1 h, 70 deg C, 2) 15 h, reflux 2: 55 percent / 2 N NaOH, NaBH4 / ethanol / 16 h / 50 °C / EtOH, Na 3: 98 percent / 20percent diisobutyl aluminium hydride / toluene; hexane / 2 h / -40 °C 4: 99 percent / p-toluenesulfonic acid, molecular sieve 4 Angstroem / diethyl ether; petroleum ether / 1 h / Ambient temperature 5: 80 percent / HCl / diethyl ether View Scheme