(4Z,7S,8R,9E,11E,13Z,15E,17S,19Z)-7,8,17-三羟基-4,9,11,13,15,19-二十二碳六烯酸合成路线 （共 11 条）
→
872993-05-0(4Z,7S,8R,9E,11E,13Z,15E,17S,19Z)-7,8,17-三羟基-4,9,11,13,15,19-二十二碳六烯酸
反应条件
1.1: tetrakis(triphenylphosphine) palladium(0); copper(l) iodide; piperidine / benzene / 2 h / 20 °C / |Inert atmosphere; |Darkness
2.1: acetyl chloride; methanol / 0 °C
3.1: water / methanol / 5 h / 50 °C
4.1: water; lithium hydroxide hydrate / methanol / 0 °C / |Inert atmosphere
4.2: |Inert atmosphere
View Scheme
参考文献
Rodriguez, Ana R.; Spur, Bernd W.
Tetrahedron Letters, 2012 , vol. 53, # 51 p. 6990 - 6994
