2-溴-4(3H)-喹唑啉酮合成路线 （共 4 条）
反应条件
sodium hydroxide in tetrahydrofuran
T=20°C; 2 h;
参考文献
Tangirala, Raghuraman; Antony, Smitha; Agama, Keli; Pommier, Yves; Curran, Dennis P.
Synlett, 2005 , # 18 art. no. Y06205ST, p. 2843 - 2846
反应条件
bromine in ethanol
2 h;
参考文献
Bowman, W. Russell; Elsegood, Mark R. J.; Stein, Tobias; Weaver, George W.
Organic and Biomolecular Chemistry, 2007 , vol. 5, # 1 p. 103 - 113
反应条件
1: 52 percent / POBr3; PhNMe2 / 4 h / 105 °C
2: 100 percent / aq. NaOH / tetrahydrofuran / 2 h / 20 °C
View Scheme
参考文献
Tangirala, Raghuraman; Antony, Smitha; Agama, Keli; Pommier, Yves; Curran, Dennis P.
Synlett, 2005 , # 18 art. no. Y06205ST, p. 2843 - 2846
反应条件
sodium hydride in N,N-dimethyl-formamide
3 h;
参考文献
Bowman, W. Russell; Elsegood, Mark R. J.; Stein, Tobias; Weaver, George W.
Organic and Biomolecular Chemistry, 2007 , vol. 5, # 1 p. 103 - 113
