3,5,6-三氯-[1,2,4]-噻嗪合成路线 （共 7 条）
反应条件
phosphorus pentachloride; N,N-diethylaniline; trichlorophosphate T=120°C; 5 h;
参考文献
JANSSEN PHARMACEUTICA N.V.; ARTS, Frank, Xavier, Jozef, Herwig
Patent: WO2006/15985 A1, 2006 ;
Location in patent: Page/Page column 62-63 ;
参考文献
Barlow, Michael G.; Sibous, Lakhdar; Tipping, Anthony E.
Tetrahedron Letters, 1992 , vol. 33, # 32 p. 4653 - 4656
反应条件
water 1.) 70 deg C, 4 d, 2.) CH2Cl2, 3 h; Yield given. Multistep reaction;
参考文献
Barlow, Michael G.; Sibous, Lakhdar; Suliman, Nadia N. E.; Tipping, Anthony E.
Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 6 p. 519 - 524
参考文献
Barlow, Michael G.; Sibous, Lakhdar; Suliman, Nadia N. E.; Tipping, Anthony E.
Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 6 p. 519 - 524
反应条件
T=70°C; 48 h; Yields of byproduct given;
参考文献
Barlow, Michael G.; Sibous, Lakhdar; Suliman, Nadia N. E.; Tipping, Anthony E.
Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 6 p. 519 - 524
反应条件
potassium fluoride
T=450°C;
参考文献
Barlow, Michael G.; Haszeldine, Robert N.; Simon, Charles; Simpkin, David J.; Ziervogel, Gerda
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1982 , p. 1251 - 1254
参考文献
Chang
Journal of Organic Chemistry, 1961 , vol. 26, p. 1118
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Chang; Ulbricht
Journal of the American Chemical Society, 1958 , vol. 80, p. 976,977
