4-氨基-2,6-二羟基嘧啶合成路线 (共 43 条)
参考文献
Journal of Organic Chemistry, , vol. 20, p. 829,833,835
反应条件
zinc dibromide in dimethyl sulfoxide T=110°C; Bohlmann-Rahtz heteroannulation; 72 h;
参考文献
Hughes, David D.; Bagley, Mark C.
Synlett, 2002 , # 8 p. 1332 - 1334
反应条件
ammonium sulfate 2 h; Heating;
参考文献
Zeng, Dewan; Belardinelli, Luiz
Patent: US2006/58322 A1, 2006 ;
Location in patent: Page/Page column 19; 12 ;
US 20060058322 A1
反应条件
1: 6-amino-2,4(1H,3H)-pyrimidinedione With ammonium sulfate; 1,1,1,3,3,3-hexamethyl-disilazane 2 h; Heating; 2: allyl bromide With iodine 2 h; Heating;
参考文献
Holschbach, Marcus H.; Wutz, Walter; Schueller, Manfred; Bier, Dirk; Coenen
Journal of Labelled Compounds and Radiopharmaceuticals, 2003 , vol. 46, # 4 p. 365 - 372
反应条件
PPA; phosphoric acid
参考文献
Robins; Hitchings
Journal of the American Chemical Society, 1958 , vol. 80, p. 3449,3454
反应条件
1: 6-amino-2,4(1H,3H)-pyrimidinedione With ammonium sulfate; lithium hexamethyldisilazane 2 h; Reflux; 2: methyl iodide in toluene 1.5 h; Reflux; 3: With water; sodium thiosulfate T=20°C;
参考文献
Rodriguez-Borges, Jose Enrique; Garcia-Mera, Xerardo; Balo, Maria Carmen; Brea, Jose; Caamano, Olga; Fernandez, Franco; Lopez, Carmen; Loza, Maria Isabel; Nieto, Maria Isabel
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 5 p. 2001 - 2009
参考文献
King; King
Journal of the Chemical Society, 1947 , p. 726,731
参考文献
King; King
Journal of the Chemical Society, 1947 , p. 726,731
参考文献
Shingare, M. S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 7 p. 714 - 715
参考文献
Shingare, M. S.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. 22, # 7 p. 714 - 715