7-氨基-4,4-二甲基-3,4-二氢-2H-喹啉-1-羧酸叔丁酯合成路线 (共 6 条)
参考文献
Vertex Pharmaceuticals Incorported
Patent: US2011/98311 A1, 2011 ;
反应条件
1: KNO3 / sulfuric acid 3: Pd-C / methanol View Scheme
反应条件
1: NaOH; LiAlH4 / tetrahydrofuran; water 2: KNO3 / sulfuric acid 4: Pd-C / methanol View Scheme
反应条件
1: AlCl3 / benzene 2: NaOH; LiAlH4 / tetrahydrofuran; water 3: KNO3 / sulfuric acid 5: Pd-C / methanol View Scheme
反应条件
1: thionyl chloride; aniline / dichloromethane; triethylamine 2: AlCl3 / benzene 3: NaOH; LiAlH4 / tetrahydrofuran; water 4: KNO3 / sulfuric acid 6: Pd-C / methanol View Scheme
反应条件
2: Pd-C / methanol View Scheme