4-(2-(二甲基氨基)乙氧基)苯基硼酸频哪醇酯合成路线 （共 4 条）
反应条件
potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in N,N-dimethyl-formamide T=100°C; 2 h; Microwave irradiation;
参考文献
UNIVERSITY HEALTH NETWORK; SAMPSON, Peter Brent; Ll, Sze-Wan; LIU, Yong; PAULS, Heinz W.; EDWARDS, Louise G.; FORREST, Bryan T.; FEHER, Miklos; PATEL, Narendra Kumar B.; PAN, Guohua
Patent: WO2010/115279 A1, 2010 ;
Location in patent: Page/Page column 187-188 ;
WO 2010/115279 A1
反应条件
sodium hydride in N,N-dimethyl-formamide; mineral oil T=60°C;
参考文献
HUTCHISON MEDIPHARMA LIMITED; Su, Wei-Guo; Deng, Wei; Ji, Jianguo
Patent: US2014/121200 A1, 2014 ;
Location in patent: Paragraph 0156; 0157 ;
反应条件
triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran T=0 - 20°C; 17 h;
参考文献
WO2006/4703 A2, ;
Page/Page column 46-47 ;
WO 2006/004703 A2
反应条件
caesium carbonate in tetrahydrofuran T=130°C; 1 h; Microwave irradiation;
参考文献
US2011/178053 A1, ;
Page/Page column 69 ;
US 20110178053 A1
