4-甲基-2-吗啉-4-嘧啶-5-羧酸合成路线 (共 2 条)
反应条件
sodium hydroxide in methanol; water
T=60°C; 2 h;
参考文献
Scott, James S.; Gill, Adrian L.; Godfrey, Linda; Groombridge, Sam D.; Rees, Amanda; Revill, John; Schofield, Paul; Soerme, Pernilla; Stocker, Andrew; Swales, John G.; Whittamore, Paul R.O.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 21 p. 6756 - 6761
反应条件
1: sodium methylate / methanol / 6 h / 80 °C
2: sodium hydroxide / methanol; water / 2 h / 60 °C
View Scheme
参考文献
Scott, James S.; Gill, Adrian L.; Godfrey, Linda; Groombridge, Sam D.; Rees, Amanda; Revill, John; Schofield, Paul; Soerme, Pernilla; Stocker, Andrew; Swales, John G.; Whittamore, Paul R.O.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 21 p. 6756 - 6761