4-氰基-5,6-二氢吡啶-1(2H)-羧酸叔丁酯合成路线 （共 2 条）
反应条件
tetrakis(triphenylphosphine) palladium(0) in dimethyl sulfoxide
T=100°C; 2 h;
参考文献
SYNGENTA PARTICIPATIONS AG; LAMBERTH, Clemens; SULZER-MOSSE, Sarah; CEDERBAUM, Fredrik; UMARYE, Jayant; SONAWANE, Ravindra
Patent: WO2013/127808 A1, 2013 ;
Location in patent: Page/Page column 31 ;
反应条件
1.1: diisopropylamine; n-butyllithium / tetrahydrofuran / 2 h / -78 °C
1.2: 5 h / -78 - -70 °C
2.1: tetrakis(triphenylphosphine) palladium(0) / dimethyl sulfoxide / 2 h / 100 °C
View Scheme
参考文献
SYNGENTA PARTICIPATIONS AG; LAMBERTH, Clemens; SULZER-MOSSE, Sarah; CEDERBAUM, Fredrik; UMARYE, Jayant; SONAWANE, Ravindra
Patent: WO2013/127808 A1, 2013 ;
