5,5'-二溴-2,2'-二碘-1,1'-联苯合成路线 （共 9 条）
反应条件
bromine; iron in chloroform
T=50°C; 24 h;
参考文献
Chan, Khai Leok; Watkins, Scott E.; Mak, Chris S. K.; McKiernan, Mary J.; Towns, Carl R.; Pascu, Sofia I.; Holmes, Andrew B.
Chemical Communications, 2005 , # 46 p. 5766 - 5768
参考文献
Cheng, Chien-Hong
Patent: US2010/253212 A1, 2010 ;
反应条件
1.1: n-butyllithium / CH2Cl2 / 24 h / -78 - 25 °C
1.2: 85 percent / iodine / CH2Cl2 / 2 h / 20 °C
2.1: 50 percent / bromine; iron / CHCl3 / 24 h / 50 °C
View Scheme
参考文献
Chan, Khai Leok; Watkins, Scott E.; Mak, Chris S. K.; McKiernan, Mary J.; Towns, Carl R.; Pascu, Sofia I.; Holmes, Andrew B.
Chemical Communications, 2005 , # 46 p. 5766 - 5768
反应条件
1.1: 87 percent / n-butyllithium / tetrahydrofuran / -78 - 25 °C
2.1: n-butyllithium / CH2Cl2 / 24 h / -78 - 25 °C
2.2: 85 percent / iodine / CH2Cl2 / 2 h / 20 °C
3.1: 50 percent / bromine; iron / CHCl3 / 24 h / 50 °C
View Scheme
参考文献
Chan, Khai Leok; Watkins, Scott E.; Mak, Chris S. K.; McKiernan, Mary J.; Towns, Carl R.; Pascu, Sofia I.; Holmes, Andrew B.
Chemical Communications, 2005 , # 46 p. 5766 - 5768
反应条件
1: With hydrogenchloride; sodium nitrite
0.5 h; cooling;
2: With potassium iodide
T=20°C; Further stages.;
参考文献
Wang, Ergang; Li, Chun; Mo, Yueqi; Zhang, Yong; Ma, Gang; Shi, Wei; Peng, Junbiao; Yang, Wei; Cao, Yong
Journal of Materials Chemistry, 2006 , vol. 16, # 42 p. 4133 - 4140
反应条件
1.1: Fe; aq. HCl / ethanol / 2 h / Heating
2.1: 13.0 g / Na2CO3 / H2O
3.1: 88 percent / N-bromosuccinimide / dimethylformamide / 12 h / 20 °C
4.1: conc. HCl / ethanol / 3 h / Heating
5.1: NaNO2; conc. HCl / 0.5 h / cooling
5.2: 4.3 g / aq. KI / 20 °C
View Scheme
参考文献
Wang, Ergang; Li, Chun; Mo, Yueqi; Zhang, Yong; Ma, Gang; Shi, Wei; Peng, Junbiao; Yang, Wei; Cao, Yong
Journal of Materials Chemistry, 2006 , vol. 16, # 42 p. 4133 - 4140
反应条件
1.1: 13.0 g / Na2CO3 / H2O
2.1: 88 percent / N-bromosuccinimide / dimethylformamide / 12 h / 20 °C
3.1: conc. HCl / ethanol / 3 h / Heating
4.1: NaNO2; conc. HCl / 0.5 h / cooling
4.2: 4.3 g / aq. KI / 20 °C
View Scheme
参考文献
Wang, Ergang; Li, Chun; Mo, Yueqi; Zhang, Yong; Ma, Gang; Shi, Wei; Peng, Junbiao; Yang, Wei; Cao, Yong
Journal of Materials Chemistry, 2006 , vol. 16, # 42 p. 4133 - 4140
反应条件
1.1: 88 percent / N-bromosuccinimide / dimethylformamide / 12 h / 20 °C
2.1: conc. HCl / ethanol / 3 h / Heating
3.1: NaNO2; conc. HCl / 0.5 h / cooling
3.2: 4.3 g / aq. KI / 20 °C
View Scheme
参考文献
Wang, Ergang; Li, Chun; Mo, Yueqi; Zhang, Yong; Ma, Gang; Shi, Wei; Peng, Junbiao; Yang, Wei; Cao, Yong
Journal of Materials Chemistry, 2006 , vol. 16, # 42 p. 4133 - 4140
反应条件
1.1: conc. HCl / ethanol / 3 h / Heating
2.1: NaNO2; conc. HCl / 0.5 h / cooling
2.2: 4.3 g / aq. KI / 20 °C
View Scheme
参考文献
Wang, Ergang; Li, Chun; Mo, Yueqi; Zhang, Yong; Ma, Gang; Shi, Wei; Peng, Junbiao; Yang, Wei; Cao, Yong
Journal of Materials Chemistry, 2006 , vol. 16, # 42 p. 4133 - 4140
