9-氧代-3-氮杂螺[5.5]-7-十一烯-3-羧酸叔丁酯合成路线 (共 2 条)
反应条件
ethanol; potassium hydroxide
T=70°C;
参考文献
WYETH
Patent: WO2009/108827 A1, 2009 ;
Location in patent: Page/Page column 38 ;
WO 2009/108827 A1
反应条件
hydrogen; palladium-on-charcoal in methanol
T=25°C; 16 h; Inert atmosphere; Product distribution / selectivity;
参考文献
Gruenenthal GmbH
Patent: US2010/249095 A1, 2010 ;
Location in patent: Page/Page column 127 ;
US 20100249095 A1