5-溴-4-甲基-2-噻唑羧酸合成路线 （共 4 条）
反应条件
1: 2,5-dibromo-4-methylthiazole With n-butyllithium in hexane
T=-70°C; 1 h;
2: carbon dioxide in hexane
参考文献
Boehringer Ingelheim (Canada) Ltd.
Patent: US2003/236251 A1, 2003 ;
Location in patent: Page 28 ;
反应条件
ammonium hydroxide
T=110°C;
参考文献
Takeda; Minato
Yakugaku Zasshi, 1951 , vol. 71, p. 1242
Chem.Abstr., 1952 , p. 5583
反应条件
ammonium hydroxide
T=110°C;
参考文献
Takeda; Minato
Yakugaku Zasshi, 1951 , vol. 71, p. 1242
Chem.Abstr., 1952 , p. 5583
反应条件
in methanol; dichloromethane
参考文献
Boehringer Ingelheim (Canada) Ltd.
Patent: US2003/236251 A1, 2003 ;
Location in patent: Page 28 ;
