in tetrahydrofuran 72 h;

n-butyllithium 1.) ether / hexane, room temperature, 1h, 2.) room temperature, 3h; Yield given. Multistep reaction;

1: 86 percent / bis-(2-methoxy-ethyl) ether / -78 °C 2: 85 percent / 1) NaH / dimethylsulfoxide; tetrahydrofuran / 1) 20 deg C, 15 min, 2) 30 min 3: 86 percent / 6percent hydrochloric acid / methanol; H2O / 0.5 h / Ambient temperature View Scheme