(2-(5-硝基-1H-吲哚-2-基)苯基)甲醇合成路线 （共 5 条）
反应条件
borane-THF in tetrahydrofuran
T=20°C; 2 h;
参考文献
Samosorn, Siritron; Bremner, John B.; Ball, Anthony; Lewis, Kim
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 3 p. 857 - 865
反应条件
1: 91 percent / DCC; DMAP / CH2Cl2 / 0 - 20 °C
2: 50 percent / acetic acid / palladium(II) acetate / 11 h / 110 °C
3: 95 percent / t-BuOK / 2-methyl-propan-2-ol; H2O / 12 h / 82 °C
4: 99 percent / BH3*THF / tetrahydrofuran / 2 h / 20 °C
View Scheme
参考文献
Samosorn, Siritron; Bremner, John B.; Ball, Anthony; Lewis, Kim
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 3 p. 857 - 865
反应条件
1: 91 percent / DCC; DMAP / CH2Cl2 / 0 - 20 °C
2: 50 percent / acetic acid / palladium(II) acetate / 11 h / 110 °C
3: 95 percent / t-BuOK / 2-methyl-propan-2-ol; H2O / 12 h / 82 °C
4: 99 percent / BH3*THF / tetrahydrofuran / 2 h / 20 °C
View Scheme
参考文献
Samosorn, Siritron; Bremner, John B.; Ball, Anthony; Lewis, Kim
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 3 p. 857 - 865
反应条件
1: 50 percent / acetic acid / palladium(II) acetate / 11 h / 110 °C
2: 95 percent / t-BuOK / 2-methyl-propan-2-ol; H2O / 12 h / 82 °C
3: 99 percent / BH3*THF / tetrahydrofuran / 2 h / 20 °C
View Scheme
参考文献
Samosorn, Siritron; Bremner, John B.; Ball, Anthony; Lewis, Kim
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 3 p. 857 - 865
反应条件
1: 95 percent / t-BuOK / 2-methyl-propan-2-ol; H2O / 12 h / 82 °C
2: 99 percent / BH3*THF / tetrahydrofuran / 2 h / 20 °C
View Scheme
参考文献
Samosorn, Siritron; Bremner, John B.; Ball, Anthony; Lewis, Kim
Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 3 p. 857 - 865
