D-(-)-alpha-苯甘氨酸合成路线 （共 142 条）
反应条件
1: 97 percent / 0.5 M aq. LiOH / methanol / 5 h / Ambient temperature 2: 78 percent / sodium naphthalenide / 1,2-dimethoxy-ethane / 0.5 h / -40 °C View Scheme
参考文献
Liebigs Annales, , # 1 p. 141 - 154
反应条件
α-amino ester hydrolase from Xanthomonas campestris pv. campestris (ATCC 33913) T=25°C; pH=6.2; aq. phosphate bufferEnzymatic reaction;
参考文献
Journal of Molecular Catalysis B: Enzymatic, , vol. 67, # 1-2 p. 21 - 28
反应条件
D-amino acid transaminase; (R)-alanine; R-selective ω-transaminase from Arthrobacter sp; (3-hydroxy-5-hydroxymethyl)-2-methylisonicotinic acid 5-phosphate; isopropylamine in aq. phosphate buffer pH=7; 12 h;
参考文献
ChemCatChem, , vol. 5, # 12 p. 3538 - 3542
反应条件
ammonia; benzonitrile
参考文献
Journal of the Chemical Society, , vol. 109, p. 1103,1105
反应条件
Rhodococcus sp. AJ270 in phosphate buffer T=30°C; pH=7.62; 2 h; Title compound not separated from byproducts;
参考文献
Tetrahedron Letters, , vol. 42, # 39 p. 6925 - 6927
反应条件
phosphate buffer; Pantoea sp. 17.3.1 permeabilized cells; Triton X-100 T=4°C; pH=7.4; 0.333333 h;
参考文献
Tetrahedron Asymmetry, , vol. 13, # 24 p. 2629 - 2633
反应条件
2: 95 percent / Zn powder, aq. 1N HCl, AcOH / 48 h / 0 °C 3: 1) 1N aq. LiOH, 2) Amberlite IR-120 / 1) THF, room temperature, 2) H2O, room temperature, 15 h View Scheme
参考文献
Helvetica Chimica Acta, , vol. 75, # 6 p. 1965 - 1978
反应条件
1: 95 percent / Zn powder, aq. 1N HCl, AcOH / 48 h / 0 °C 2: 1) 1N aq. LiOH, 2) Amberlite IR-120 / 1) THF, room temperature, 2) H2O, room temperature, 15 h View Scheme
参考文献
Helvetica Chimica Acta, , vol. 75, # 6 p. 1965 - 1978
反应条件
1.1: hydrogenchloride; palladium 10 on activated carbon; hydrogen / methanol; water / 16 h / 20 °C / 760.05 Torr 2.1: hydrogenchloride; water / 0.17 h / 150 °C / Inert atmosphere; Microwave irradiation 2.2: DOWEX 50W-X8 ion-exchange column View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 22, # 12 p. 1274 - 1281
反应条件
1.1: hydrogenchloride; water / ethanol / 0.08 h / 130 °C / Inert atmosphere; Microwave irradiation 2.1: hydrogenchloride; palladium 10 on activated carbon; hydrogen / methanol; water / 16 h / 20 °C / 760.05 Torr 3.1: hydrogenchloride; water / 0.17 h / 150 °C / Inert atmosphere; Microwave irradiation 3.2: DOWEX 50W-X8 ion-exchange column View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 22, # 12 p. 1274 - 1281
