1: 4-Chlorothieno[3,2-d]pyrimidine With lithium diisopropyl amide in tetrahydrofuran; n-heptane; ethylbenzene T=-78°C; 0.5 h; 2: tributyltin chloride in tetrahydrofuran; n-heptane; ethylbenzene T=-78°C; 2.33333 h;