4-甲基-9H-噻吨-9-酮合成路线 （共 7 条）
反应条件
sulfuric acid
T=100°C; 1 h;
参考文献
Filippatos; Papadaki-Valiraki; Roussakis; Verbist
Archiv der Pharmazie, 1993 , vol. 326, # 8 p. 451 - 456
反应条件
1: K2CO3, KI, Cu / dimethylformamide / Heating
2: conc. H2SO4 / Heating
View Scheme
参考文献
Filippatos; Papadaki-Valiraki; Todoulou; Jacquemin-Sablon
Archiv der Pharmazie, 1994 , vol. 327, # 2 p. 61 - 66
反应条件
1: K2CO3, KI, Cu / dimethylformamide / Heating
2: conc. H2SO4 / Heating
View Scheme
参考文献
Filippatos; Papadaki-Valiraki; Todoulou; Jacquemin-Sablon
Archiv der Pharmazie, 1994 , vol. 327, # 2 p. 61 - 66
反应条件
1: 75 percent / potassium carbonate, copper I iodide, copper bronz / nitrobenzene
2: 66 percent / sulfuric acid
View Scheme
参考文献
Brindle, Ian D.; Doyle, Paul P.
Canadian Journal of Chemistry, 1983 , vol. 61, p. 1869 - 1871
反应条件
1: 75 percent / potassium carbonate, copper I iodide, copper bronz / nitrobenzene
2: 66 percent / sulfuric acid
View Scheme
参考文献
Brindle, Ian D.; Doyle, Paul P.
Canadian Journal of Chemistry, 1983 , vol. 61, p. 1869 - 1871
反应条件
1.1: potassium hydroxide; copper / N,N-dimethyl-formamide / 5 h / 130 °C
1.2: 0.5 h / 25 °C
2.1: sulfuric acid / 7 h / 60 °C
View Scheme
参考文献
San-Apro Limited
Patent: US8329771 B2, 2012 ;
参考文献
Brindle, Ian D.; Doyle, Paul P.
Canadian Journal of Chemistry, 1983 , vol. 61, p. 1869 - 1871
