2-甲基噁唑-4-羧酸 N-甲氧基-N-甲酰胺合成路线 （共 3 条）
参考文献
Benoit, Georges-Emmanuel; Carey, John S.; Chapman, Alan M.; Chima, Ranjit; Hussain, Nigel; Popkin, Matthew E.; Roux, Guillaume; Tavassoli, Bahareh; Vaxelaire, Carine; Webb, Michael R.; Whatrup, David
Organic Process Research and Development, 2008 , vol. 12, # 1 p. 88 - 95
反应条件
1: With triethylamine in dichloromethane; water
T=20°C; 1 h; Large scale;
2: With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in dichloromethane
T=0 - 20°C; 1 h; Large scale;
参考文献
Benoit, Georges-Emmanuel; Carey, John S.; Chapman, Alan M.; Chima, Ranjit; Hussain, Nigel; Popkin, Matthew E.; Roux, Guillaume; Tavassoli, Bahareh; Vaxelaire, Carine; Webb, Michael R.; Whatrup, David
Organic Process Research and Development, 2008 , vol. 12, # 1 p. 88 - 95
反应条件
1.1: water; sodium hydroxide / 1 h / 20 - 25 °C / |Large scale
2.1: triethylamine / dichloromethane; water / 1 h / 20 °C / |Large scale
2.2: 1 h / 0 - 20 °C / |Large scale
View Scheme
参考文献
Benoit, Georges-Emmanuel; Carey, John S.; Chapman, Alan M.; Chima, Ranjit; Hussain, Nigel; Popkin, Matthew E.; Roux, Guillaume; Tavassoli, Bahareh; Vaxelaire, Carine; Webb, Michael R.; Whatrup, David
Organic Process Research and Development, 2008 , vol. 12, # 1 p. 88 - 95
