1: dl-2-phenyloxetane With sec.-butyllithium in tetrahydrofuran; cyclohexane T=-78°C; 0.0833333 h; Inert atmosphere; 2: ethyl iodide in tetrahydrofuran; cyclohexane T=-78°C; Inert atmosphere; regioselective reaction;

1.1: potassium tert-butylate / tetrahydrofuran / 4 h / 25 °C 2.1: sec.-butyllithium / tetrahydrofuran; cyclohexane / 0.08 h / -78 °C / Inert atmosphere 2.2: -78 °C / Inert atmosphere View Scheme