(1S,3R)-环戊烷-1,3-二甲酸合成路线 （共 33 条）
反应条件
1: 61 percent / Br2, HgO, MgSO4 / CH2Cl2 / 2 h / Heating; Irradiation 2: 15 percent / Pr4NBr / dimethylformamide / electrolytic reduction: platinum electrodes; reference: Ag wire. cathode and anode separated by a membrane View Scheme
参考文献
Hoffmann, Joachim; Voss, Juergen
Chemische Berichte, 1992 , vol. 125, # 6 p. 1415 - 1420
反应条件
1: 91 percent / Dowex H+ resin / Heating 2: phosphate buffer / acetonitrile / 37 °C / pH 7.0, cholesterol esterase 3: Et3N / acetone / -5 °C 4: NaN3 / H2O / -5 °C 5: toluene / Heating View Scheme
参考文献
Chenevert; Martin
Tetrahedron Asymmetry, 1992 , vol. 3, # 2 p. 199 - 200
反应条件
1: 79 percent / acetic anhydride / 0.5 h / Heating
2: 1.) r.t., 19 h; 2.) 2 deg C, 12 days
3: 26.2 g / thionyl chloride, pyridine, DMF / benzene / 2 h / Heating
View Scheme
参考文献
Guha; Ranganathan
Chemische Berichte, 1936 , vol. 69, p. 1195,1198
