2,4-双-(氰基甲基)-2,4,6-三甲基苯合成路线 （共 7 条）
反应条件
sulfuric acid; water 12 h; Heating;
参考文献
Alcalde, Ermitas; Ceder, Rosa M.; Lopez, Cristina; Mesquida, Neus; Muller, Guillermo; Rodriguez, Sandra
Dalton Transactions, 2007 , # 25 p. 2696 - 2706
反应条件
1: in dimethyl sulfoxide
T=20°C; Substitution; 12 h;
2: With sodium azide
T=80°C; Substitution; 3 h;
3: With water; triphenylphosphine in tetrahydrofuran
Reduction; 4 h; Heating;
参考文献
Wu, Chengde; Decker, E. Radford; Blok, Natalie; Bui, Huong; Chen, Qi; Raju; Bourgoyne, Andree R.; Knowles, Vippra; Biediger, Ronald J.; Market, Robert V.; Lin, Shuqun; Dupre, Brian; Kogan, Timothy P.; Holland, George W.; Brock, Tommy A.; Dixon, Richard A. F.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 22 p. 4485 - 4499
反应条件
in dimethyl sulfoxide
参考文献
Alcalde, Ermitas; Dinares, Immaculada; Mesquida, Neus; Rodriguez, Sandra
Synthesis, 2007 , # 6 p. 865 - 872
Title/Abstract Full Text View citing articles Show Details
Alcalde, Ermitas; Ceder, Rosa M.; Lopez, Cristina; Mesquida, Neus; Muller, Guillermo; Rodriguez, Sandra
Dalton Transactions, 2007 , # 25 p. 2696 - 2706
反应条件
1: in dimethyl sulfoxide
T=20°C; Substitution; 12 h;
2: With sodium azide
T=80°C; Substitution; 3 h; Title compound not separated from byproducts;
参考文献
Wu, Chengde; Decker, E. Radford; Blok, Natalie; Bui, Huong; Chen, Qi; Raju; Bourgoyne, Andree R.; Knowles, Vippra; Biediger, Ronald J.; Market, Robert V.; Lin, Shuqun; Dupre, Brian; Kogan, Timothy P.; Holland, George W.; Brock, Tommy A.; Dixon, Richard A. F.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 22 p. 4485 - 4499
反应条件
in methanol; water
5 h; Heating;
参考文献
Chung, Yun Mi; Raman, Balamurali; Ahn, Kyo Han
Tetrahedron, 2006 , vol. 62, # 50 p. 11645 - 11651
反应条件
in dimethyl sulfoxide
T=20°C; Substitution; 12 h; Title compound not separated from byproducts;
参考文献
Wu, Chengde; Decker, E. Radford; Blok, Natalie; Bui, Huong; Chen, Qi; Raju; Bourgoyne, Andree R.; Knowles, Vippra; Biediger, Ronald J.; Market, Robert V.; Lin, Shuqun; Dupre, Brian; Kogan, Timothy P.; Holland, George W.; Brock, Tommy A.; Dixon, Richard A. F.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 22 p. 4485 - 4499
参考文献
Krivykh, V. V.; Tolstaya, M. V.; Rybinskaya, M. I.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1986 , vol. 35, # 10 p. 2155 - 2157
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1986 , # 10 p. 2353 - 2356
