1-(三异丙基硅烷)吡咯合成路线 （共 41 条）
反应条件
n-butyllithium in tetrahydrofuran; hexane T=-78 - 20°C;
参考文献
Fuchi, Nobuhiro; Iura, Yosuke; Kaneko, Hiroaki; Nitta, Aiko; Suyama, Kazuharu; Ueda, Hiroshi; Yamaguchi, Shinichi; Nishimura, Kazumi; Fujii, Shigeo; Sekiya, Yumiko; Yamada, Masateru; Takahashi, Toshiya
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 13 p. 4358 - 4361
反应条件
n-butyllithium; dimethyl-(4-nitro-buta-1,3-dienyl)-amine in tetrahydrofuran; pentane T=-78 - 20°C; Dehalogenation;
参考文献
Koike, Takeshi; Shinohara, Yoshifumi; Nishimura, Takeshi; Hagiwara, Masanori; Tobinaga, Seisho; Takeuchi, Naoki
Heterocycles, 2000 , vol. 53, # 6 p. 1351 - 1359
反应条件
1: 3-bromo-1-(triisopropylsilyl)pyrrole With tert.-butyl lithium in tetrahydrofuran; pentane T=-78°C; Metallation; 0.333333 h; 2: tert-nitrodienamine in tetrahydrofuran T=-78 - 20°C; Alkylation;
参考文献
Heterocycles, , vol. 53, # 6 p. 1351 - 1359
反应条件
1: With tert.-butyl lithium in tetrahydrofuran T=-80°C; 0.166667 h; Schlenk techniqueInert atmosphere; 2: With methanol in tetrahydrofuran T=-75°C; Inert atmosphereSchlenk technique;
参考文献
Organic Letters, , vol. 15, # 12 p. 2954 - 2957
参考文献
Journal of the American Chemical Society, , vol. 112, # 6 p. 2439 - 2440
Journal of Physical Chemistry, , vol. 95, # 24 p. 10158 - 10164
反应条件
n-butyllithium; tetrabutyl ammonium fluoride 1.) THF, hexane, -23 deg C, 2 h, 2.) THF; Multistep reaction;
参考文献
Kozikowski, Alan P.; Cheng, Xue-Min
Journal of Organic Chemistry, 1984 , vol. 49, # 17 p. 3239 - 3240
反应条件
n-butyllithium 1.) THF, hexane, -23 deg C, 2 h; Yield given. Multistep reaction;
参考文献
Kozikowski, Alan P.; Cheng, Xue-Min
Journal of Organic Chemistry, 1984 , vol. 49, # 17 p. 3239 - 3240
反应条件
n-butyllithium 1.) THF, hexane, -23 deg C, 2 h; Yield given. Multistep reaction;
参考文献
Kozikowski, Alan P.; Cheng, Xue-Min
Journal of Organic Chemistry, 1984 , vol. 49, # 17 p. 3239 - 3240
反应条件
n-butyllithium; N-fluoro-N-(phenylsulfonyl)benzene-sulfonamide 1.) THF, hexane, -78 deg C, 0.5 h, 2.) THF, hexane, a) -78 deg C, 0.5 h, b) RT, overnight; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Synthetic Communications, , vol. 24, # 12 p. 1749 - 1755
反应条件
toluene-4-sulfonic acid in toluene Heating;
参考文献
Smith, Jonathan O.; Mandal, Braja K.
Journal of Heterocyclic Chemistry, 1997 , vol. 34, # 5 p. 1441 - 1446
