1-(三异丙基硅烷)吡咯合成路线 （共 41 条）
反应条件
N-bromosuccinmide in tetrahydrofuran; water
参考文献
Boehringer Ingelheim Pharmaceuticals, Inc.
Patent: US5837704 A1, 1998 ;
反应条件
acetic anhydride; copper(II) nitrate T=25°C; 1 h;
参考文献
Journal of Organic Chemistry, , vol. 55, # 26 p. 6317 - 6328
反应条件
1: With oxalyl dichloride in dichloromethane Vilsmeier-Haack formylation; 0.5 h; Heating; 2: With sodium hydroxide T=20°C; 20 h;
参考文献
Purkarthofer, Thomas; Gruber, Karl; Fechter, Martin H.; Griengl, Herfried
Tetrahedron, 2005 , vol. 61, # 32 p. 7661 - 7668
参考文献
Beecher, Jody E.; Tirrell, David A.
Tetrahedron Letters, 1998 , vol. 39, # 23 p. 3927 - 3930
反应条件
sodium hydroxide; diphosphoric acid tetrachloride 1) acetonitrile, 20 deg C, 2 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Downie, Ian M.; Earle, Martyn J.; Heaney, Harry; Shuhaibar, Khamis F.
Tetrahedron, 1993 , vol. 49, # 19 p. 4015 - 4034
反应条件
sodium hydroxide; diphosphoric acid tetrachloride 1) acetonitrile, 20 deg C, 2 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Downie, Ian M.; Earle, Martyn J.; Heaney, Harry; Shuhaibar, Khamis F.
Tetrahedron, 1993 , vol. 49, # 19 p. 4015 - 4034
反应条件
sodium hydroxide; diphosphoric acid tetrachloride 1) acetonitrile, 20 deg C, 2 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Tetrahedron, , vol. 49, # 19 p. 4015 - 4034
反应条件
sodium hydroxide; diphosphoric acid tetrachloride 1) acetonitrile, 20 deg C, 2 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Tetrahedron, , vol. 49, # 19 p. 4015 - 4034
反应条件
trifluoroacetic acid AcOH/CH2Cl2, room temp., 48 h, then after evaporation CH2Cl2, 150 deg C,1 h;
参考文献
Liebigs Annalen der Chemie, , p. 491 - 494
反应条件
1.1: 88 percent / NBS / tetrahydrofuran / -78 °C 2.1: n-BuLi / tetrahydrofuran / -78 °C 2.2: B(OCH3)3 2.3: 50 percent / aq. MeOH View Scheme
参考文献
Curis, Inc.; Bao, Rudi; Lai, Chengjung; Qian, Changgeng
Patent: US2013/102595 A1, 2013 ;
