1-(三异丙基硅烷)吡咯合成路线 （共 41 条）
反应条件
1: 95 percent / NBS, hydroquinone / acetone / 1 h / Heating 2: 1.) BuLi / 1.) THF, hexane, 2 - 3 min; 2.) 2 h, RT View Scheme
参考文献
Iyoda, Tomokazu; Aiba, Masaji; Saika, Tetsuyuki; Honda, Kenichi; Shimidzu, Takeo
Journal of the Chemical Society, Faraday Transactions, 1991 , vol. 87, # 11 p. 1765 - 1770
反应条件
pyridine in dichloromethane
48 h; Ambient temperature;
参考文献
Bray, Brian L.; Mathies, Peter H.; Naef, Reto; Solas, Dennis R.; Tidwell, Thomas T.; et al.
Journal of Organic Chemistry, 1990 , vol. 55, # 26 p. 6317 - 6328
反应条件
copper(II) nitrate in acetic anhydride
2 h; Ambient temperature;
参考文献
Muchowski, Joseph M.; Solas, Dennis R.
Tetrahedron Letters, 1983 , vol. 24, # 33 p. 3455 - 3456
反应条件
acetic anhydride; copper(II) nitrate
T=25°C; 1 h;
参考文献
Bray, Brian L.; Mathies, Peter H.; Naef, Reto; Solas, Dennis R.; Tidwell, Thomas T.; et al.
Journal of Organic Chemistry, 1990 , vol. 55, # 26 p. 6317 - 6328
反应条件
1: 95 percent / NBS, hydroquinone / acetone / 1 h / Heating
2: 1.) BuLi / 1.) THF, hexane, 2 - 3 min; 2.) 2 h, RT
View Scheme
参考文献
Kozikowski, Alan P.; Cheng, Xue-Min
Journal of Organic Chemistry, 1984 , vol. 49, # 17 p. 3239 - 3240
反应条件
1: 90 percent / NBS / tetrahydrofuran / -78 - 20 °C
2: 1.) n-BuLi / 1.) THF, hexane, -23 deg C, 2 h
View Scheme
参考文献
Kozikowski, Alan P.; Cheng, Xue-Min
Journal of Organic Chemistry, 1984 , vol. 49, # 17 p. 3239 - 3240
反应条件
N-bromosuccinmide in tetrahydrofuran
T=-78°C; 0.5 h;
参考文献
Higashino, Tomohiro; Osuka, Atsuhiro
Chemistry - An Asian Journal, 2013 , vol. 8, # 9 p. 1994 - 2002
反应条件
N-bromosuccinmide in tetrahydrofuran
T=-78°C; 1 h; Yields of byproduct given;
参考文献
Bray, Brian L.; Mathies, Peter H.; Naef, Reto; Solas, Dennis R.; Tidwell, Thomas T.; et al.
Journal of Organic Chemistry, 1990 , vol. 55, # 26 p. 6317 - 6328
反应条件
N-bromosuccinmide in tetrahydrofuran
T=23°C; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Bray, Brian L.; Mathies, Peter H.; Naef, Reto; Solas, Dennis R.; Tidwell, Thomas T.; et al.
Journal of Organic Chemistry, 1990 , vol. 55, # 26 p. 6317 - 6328
反应条件
N-bromosuccinmide in tetrahydrofuran
T=-78°C; Yield given. Yields of byproduct given;
参考文献
Muchowski, Joseph M.; Naef, Reto
Helvetica Chimica Acta, 1984 , vol. 67, p. 1168 - 1172
