1,2,3-Benzotriazole; potassium phosphate; copper(l) iodide in dimethyl sulfoxide T=120°C; 24 h; Inert atmosphere;

1,2,3-Benzotriazole; potassium phosphate; copper(l) iodide in dimethyl sulfoxide T=120°C; 24 h; Inert atmosphere; optical yield given as percent deregioselective reaction;

iodine; sodium hydrogencarbonate in acetonitrile T=0°C; 1 h;

copper(l) iodide; 1-Hydroxymethyl-1H-benzotriazole; potassium tert-butylate in dimethyl sulfoxide T=120°C; 18 h; Inert atmosphere;

1: 80 percent / diethyl ether / 0.5 h / 0 °C 2: 83 percent / 3 h / 250 °C 3: 76 percent / sodium hydrogencarbonate; iodine / acetonitrile / 1 h / 0 °C View Scheme

1: 83 percent / 3 h / 250 °C 2: 76 percent / sodium hydrogencarbonate; iodine / acetonitrile / 1 h / 0 °C View Scheme

1: tris-(dibenzylideneacetone)dipalladium(0); 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl; sodium tert-pentoxide / 1,4-dioxane / 12 h / 110 °C / |Inert atmosphere 2: Ru(bpz)3(PF6)2 / acetonitrile / 2 h / 20 °C / |Irradiation; |Inert atmosphere View Scheme