1: With benzotriazol-1-ol; dicyclohexyl-carbodiimide in dichloromethane T=20 - 25°C; 3 h; 2: With hydrogen; palladium 10 on activated carbon in isopropyl alcohol T=25 - 35°C; P=1471.14 - 2206.72 Torr; 3: With diethyl ether 0.0833333 - 0.166667 h;

1: With benzotriazol-1-ol; dicyclohexyl-carbodiimide in dichloromethane T=20 - 25°C; 3 h; 2: With hydrogen; palladium 10 on activated carbon in isopropyl alcohol T=25 - 35°C; P=1471.14 - 2206.72 Torr;

hydrogen; palladium 10 on activated carbon in ethanol T=10°C; P=1125.11 Torr; 1.5 - 5 h; Product distribution / selectivity;

1: phenylmethyl-(2S,3aR,7aS)-octahydroindole-2-carboxylate hydrochloride With sodium hydroxide in dichloromethane; water 1 h; 2: (2S)-2-[N-((1S)-1-ethoxycarbonyl-3-phenylpropyl)amino]propionic acid With benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide in dichloromethane T=20°C; 20.25 h; 3: With hydrogen; palladium 10 on activated carbon in ethanol P=1500.15 Torr; Product distribution / selectivity;

1: octahydroindole-2-carboxylic acid benzyl ester hydrochloride With sodium hydroxide in dichloromethane; water 1 h; 2: N-[(S)-1-carbethoxy-3-phenyl-propyl]-S-alaninoyl chloride hydrochloride With triethylamine in dichloromethane T=20°C; 3 h; 3: With hydrogen; palladium 10 on activated carbon in ethanol P=1500.15 Torr; Product distribution / selectivity;

1: phenylmethyl-(2S,3aR,7aS)-octahydroindole-2-carboxylate hydrochloride With sodium hydroxide in dichloromethane; water 1 h; 2: N-[(S)-1-carbethoxy-3-phenyl-propyl]-S-alaninoyl chloride hydrochloride With triethylamine in dichloromethane T=20°C; 3 h; 3: With hydrogen; palladium 10 on activated carbon in ethanol P=1500.15 Torr; Product distribution / selectivity;

1: (2S,3aR,7aS)-octahydroindolecarboxylic acid With triethylamine in dichloromethane T=20°C; 0.5 h; 2: N-[1-(S)-ethoxycarbonyl-3-phenylpropyl]-L-alanine N-carboxyanhydride in dichloromethane T=20°C; 3 h; 3: With hydrogenchloride in dichloromethane; water T=15°C; pH=4.2; Product distribution / selectivity;

1: in dichloromethane T=0 - 5°C; 2 h; 2: With acetic acid in water Product distribution / selectivity;

1: With 1H-imidazole in dichloromethane T=-5 - 30°C; 1.5 h; 2: With acetic acid in water T=10 - 30°C; 0.25 h; Product distribution / selectivity;

1: N-[(S)-1-carbethoxy-3-phenyl-propyl]-S-alaninoyl chloride hydrochloride With 1H-imidazole in dichloromethane T=-5 - 0°C; 1 h; 2: (2S,3aR,7aS)-octahydroindolecarboxylic acid in dichloromethane T=-5 - 25°C; 4.75 h; 3: With acetic acid in dichloromethane; water T=5°C; 0.5 h; Product distribution / selectivity;