BOC-PHE-甲氧基甲胺合成路线 （共 25 条）
反应条件
O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine in dichloromethane
参考文献
Capela, Rita; Oliveira, Rudi; Goncalves, Lidia M.; Domingos, Ana; Gut, Jiri; Rosenthal, Philip J.; Lopes, Francisca; Moreira, Rui
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 12 p. 3229 - 3232
反应条件
benzotriazol-1-ol; N'-(3-dimethylaminopropyl)-N-ethylcarbodiimide; N-ethyl-N,N-diisopropylamine in acetonitrile Acylation;
参考文献
Ko, Eunhwa; Liu, Jing; Perez, Lisa M.; Lu, Genliang; Schaefer, Amber; Burgess, Kevin
Journal of the American Chemical Society, 2011 , vol. 133, # 3 p. 462 - 477
反应条件
triethylamine; Sm(OTf)3 in tetrahydrofuran T=20°C; 72 h;
参考文献
Sibi, Mukund P.; Hasegawa, Hikaru; Ghorpade, Sandeep R.
Organic Letters, 2002 , vol. 4, # 20 p. 3343 - 3346
反应条件
zirconium tetrachloride in dichloromethane; acetonitrile T=23°C; 1 h;
参考文献
Dineen, Thomas A.; Zajac, Matthew A.; Myers, Andrew G.
Journal of the American Chemical Society, 2006 , vol. 128, # 50 p. 16406 - 16409
反应条件
4-methyl-morpholine in dichloromethane
参考文献
Tetrahedron Letters, , vol. 35, # 19 p. 3183 - 3186
反应条件
benzotriazol-1-ol in N,N-dimethyl-formamide
参考文献
US5859012 A1, ;
US 5859012 A
反应条件
1: 5 Angstroem molecular sieves / CH2Cl2 / 4 h / Heating 2: 55.6 mg / ZrCl4 / acetonitrile; CH2Cl2 / 1 h / 23 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 128, # 50 p. 16406 - 16409
反应条件
in dichloromethane T=10 - 20°C; 4 h; Yield given;
参考文献
European Journal of Medicinal Chemistry, , vol. 28, # 1 p. 47 - 61
反应条件
triethylamine in dichloromethane 1.) 0 deg C, 30 min, 2.) r.t., 20 h; Yield given;
参考文献
Journal of Organic Chemistry, , vol. 60, # 6 p. 1727 - 1732
