BOC-PHE-甲氧基甲胺合成路线 （共 25 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=-78°C; Reduction;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 10, # 20 p. 2305 - 2309
反应条件
lithium aluminium tetrahydride in diethyl ether T=-50°C; 0.333333 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 56, # 13 p. 4161 - 4167
反应条件
1: tetrahydrofuran 2: lithium hexamethyldisilazane / tetrahydrofuran 3: N-bromosuccinmide / tetrahydrofuran / -40 °C 4: sodium tetrahydroborate / ethanol / -78 °C 5: potassium hydroxide / ethanol View Scheme
参考文献
Chemistry - A European Journal, , vol. 17, # 52 p. 14772 - 14784
反应条件
1: 83 percent / LiAlH4 / diethyl ether / 0.33 h / Ambient temperature 2: 85 percent / dimethylsulfoxide; tetrahydrofuran / 1.) -78 deg C, 15 min, 2.) 40 deg C, 12 h View Scheme
参考文献
Garro-Helion, Florence; Guibe, Francois
Chemical Communications, 1996 , # 5 p. 641 - 642
反应条件
1: LiAlH4 / tetrahydrofuran
2: CH2Cl2
3: TFA / CH2Cl2
View Scheme
参考文献
Hagihara, Masahiko; Anthony, Neville J.; Stout, Thomas J.; Clardy, Jon; Schreiber, Stuart L.
Journal of the American Chemical Society, 1992 , vol. 114, # l6 p. 6568 - 6570
