1: n-Bu3SnH; AIBN / toluene / Heating 2: 90 percent / dimethyldioxirane / acetone / 18 h / 0 - 3 °C 3: 35 percent / Dess-Martin periodinane / CH2Cl2 / 20 °C 4: 95 percent / aq. NaClO2; NaH2PO4; HOSO2NH2 / 2-methyl-propan-2-ol / 20 °C 5: 74 percent / NaOMe / methanol / 20 °C 6: 45 percent / bis(2-oxo-3-oxazolidinyl)phosphinic chloride; Et3N / CH2Cl2 / 20 °C View Scheme

1: n-Bu3SnH; AIBN / toluene / Heating 2: 90 percent / dimethyldioxirane / acetone / 18 h / 0 - 3 °C 3: 35 percent / Dess-Martin periodinane / CH2Cl2 / 20 °C 4: 95 percent / aq. NaClO2; NaH2PO4; HOSO2NH2 / 2-methyl-propan-2-ol / 20 °C 5: 74 percent / NaOMe / methanol / 20 °C View Scheme