4-(3,3-二氟吡咯烷-1-基)哌啶-1-羧酸叔丁酯合成路线 （共 1 条）
反应条件
1: With titanium(IV) isopropylate in tetrahydrofuran
T=20°C; 1 h;
2: With sodium cyanoborohydride in tetrahydrofuran; ethanol
17 h;
3: With sodium hydrogencarbonate in tetrahydrofuran; ethanol; water
参考文献
NOVARTIS AG; NOVARTIS PHARMA GMBH
Patent: WO2006/18284 A1, 2006 ;
Location in patent: Page/Page column 40-41 ;
WO 2006/018284 A1
