1-溴-4-叔丁基二甲基硅烷氧甲基苯合成路线 （共 23 条）
反应条件
n-butyllithium in diethyl ether
T=-78°C;
参考文献
Richardson, Stewart K.; Ife, Robert J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 1172 - 1174
反应条件
1: 1) n-BuLi / 1) hexane, ether, -30 to 0 deg C in 2 h, 2) ether, -50 deg C, 3 h
2: 93 percent / NH3OHCl, NaOH / ethanol / 16 h / Heating
3: 70 percent / pyridine / 3 h / Heating
4: 86 percent / liq. NH3 / diethyl ether / 12 h / Ambient temperature
View Scheme
参考文献
Richardson, Stewart K.; Ife, Robert J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 1172 - 1174
反应条件
1: in tetrahydrofuran; toluene
T=20°C; 0.5 h; Inert atmosphere;
2: With n-hexyl lithium in tetrahydrofuran; hexane; toluene
T=-78 - -20°C;
参考文献
Magnus, Nicholas A.; Anzeveno, Peter B.; Coffey, D. Scott; Hay, David A.; Laurila, Michael E.; Schkeryantz, Jeffrey M.; Shaw, Bruce W.; Staszak, Michael A.
Organic Process Research and Development, 2007 , vol. 11, # 3 p. 560 - 567
