3-(三氟甲基)-n-(2,2-二甲氧基乙基)-1H-吡唑-5-羧酰胺合成路线 （共 2 条）
反应条件
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine in dichloromethane
T=20°C; 20 h;
参考文献
MERCK and CO., INC.
Patent: WO2006/23750 A2, 2006 ;
Location in patent: Page/Page column 63 ;
WO 2006/023750 A2
反应条件
1: With trifluoroacetic acid in dichloromethane
T=20°C;
2: With PPA
T=145°C; 4.5 h;
参考文献
MERCK and CO., INC.
Patent: WO2006/23750 A2, 2006 ;
Location in patent: Page/Page column 63 ;
WO 2006/023750 A2
