2-(三氟甲基)吡唑并[1,5-a]吡嗪-4-醇合成路线 (共 2 条)
反应条件
1: With trifluoroacetic acid in dichloromethane
T=20°C;
2: With PPA
T=145°C; 4.5 h;
参考文献
MERCK and CO., INC.
Patent: WO2006/23750 A2, 2006 ;
Location in patent: Page/Page column 63 ;
WO 2006/023750 A2
反应条件
N,N-diethylaniline; trichlorophosphate
15 h; Heating / reflux;
参考文献
MERCK and CO., INC.
Patent: WO2006/23750 A2, 2006 ;
Location in patent: Page/Page column 63 ;
WO 2006/023750 A2