N-苄氧羰基-4-O-苄基多巴胺合成路线 （共 8 条）
反应条件
1: diethyl ether 2: H2 / Pd/C / ethanol View Scheme
参考文献
Casagrande; Santangelo; Saini; Doggi; Gerli; Cerri
Arzneimittel-Forschung/Drug Research, 1986 , vol. 36, # 2 A p. 291 - 303
反应条件
sodium hydrogencarbonate in ethanol
16 h; Heating;
参考文献
Casagrande; Santangelo; Saini; Doggi; Gerli; Cerri
Arzneimittel-Forschung/Drug Research, 1986 , vol. 36, # 2 A p. 291 - 303
反应条件
1: triethylamine / dimethylformamide / 4 h / ice bath
2: tert-BuOK / dimethylformamide / 6 h
View Scheme
参考文献
Konishi-Imamura; Kim; Kobashi
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 11 p. 2994 - 2998
反应条件
1: triethylamine / dimethylformamide / 4 h / ice bath
2: tert-BuOK / dimethylformamide / 6 h
View Scheme
参考文献
Konishi-Imamura; Kim; Kobashi
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 11 p. 2994 - 2998
反应条件
potassium tert-butylate in N,N-dimethyl-formamide
6 h;
参考文献
Konishi-Imamura; Kim; Kobashi
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 11 p. 2994 - 2998
反应条件
1: 2 N NaOH / toluene; H2O / 2 h / 5 - 10 °C
2: 13 percent / NaHCO3 / ethanol / 16 h / Heating
View Scheme
参考文献
Casagrande; Santangelo; Saini; Doggi; Gerli; Cerri
Arzneimittel-Forschung/Drug Research, 1986 , vol. 36, # 2 A p. 291 - 303
反应条件
1: diethyl ether
2: H2 / Pd/C / ethanol
3: 5 h / Heating
View Scheme
参考文献
Casagrande; Santangelo; Saini; Doggi; Gerli; Cerri
Arzneimittel-Forschung/Drug Research, 1986 , vol. 36, # 2 A p. 291 - 303
反应条件
1: 1.) NaH, 2.) Me3N*SO3 / DMF, 1.) 30 min, room temp., 2.) 30 min
2: H2 / 10 percent Pd/C / ethanol / 0.5 h / 2280.2 - 3037.7 Torr
View Scheme
参考文献
Konishi-Imamura; Kim; Kobashi
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 11 p. 2994 - 2998
