7-氯-2-[[[(1S)-2,2-二甲基环丙基]羰基]氨基]-2-庚烯酸合成路线 (共 2 条)
反应条件
1: With sodium hydroxide in methanol Reflux; 2: in water; butan-1-ol T=25 - 30°C; pH=3 - 3.5;
参考文献
ORCHID CHEMICALS and PHARMACEUTICALS LIMITED
Patent: US2012/253066 A1, 2012 ;
Location in patent: Page/Page column 4 ;
反应条件
sodium hydroxide in water T=20°C;
参考文献
ORCHID CHEMICALS and PHARMACEUTICALS LIMITED ORCHID TOWERS
Patent: US2009/143614 A1, 2009 ;
Location in patent: Page/Page column 4 ;