4-(氰基甲基)-4-(4-甲氧基苯基)哌啶-1-羧酸叔丁酯合成路线 （共 4 条）
反应条件
copper(I) oxide in acetonitrile
0.5 h; Heating;
参考文献
Chauder, Brian A.; Boros, Eric E.; Du, Kien S.; Kazmierski, Wieslaw M.; Koble, Cecilia S.; Thompson, James B.; Tabet, Elie A.
Synthetic Communications, 2006 , vol. 36, # 3 p. 279 - 284
反应条件
1.1: magnesium / tetrahydrofuran / 20 °C
1.2: copper(I) iodide / tetrahydrofuran / 0 - 20 °C
2.1: sodium hydroxide / ethanol; H2O / 6.5 h / 20 °C
3.1: copper(I) oxide / acetonitrile / 0.5 h / Heating
View Scheme
参考文献
Chauder, Brian A.; Boros, Eric E.; Du, Kien S.; Kazmierski, Wieslaw M.; Koble, Cecilia S.; Thompson, James B.; Tabet, Elie A.
Synthetic Communications, 2006 , vol. 36, # 3 p. 279 - 284
反应条件
1.1: magnesium / tetrahydrofuran / 20 °C
1.2: copper(I) iodide / tetrahydrofuran / 0 - 20 °C
2.1: sodium hydroxide / ethanol; H2O / 6.5 h / 20 °C
3.1: copper(I) oxide / acetonitrile / 0.5 h / Heating
View Scheme
参考文献
Chauder, Brian A.; Boros, Eric E.; Du, Kien S.; Kazmierski, Wieslaw M.; Koble, Cecilia S.; Thompson, James B.; Tabet, Elie A.
Synthetic Communications, 2006 , vol. 36, # 3 p. 279 - 284
反应条件
1.1: 100 percent / NH4OAc; AcOH; benzene
2.1: magnesium / tetrahydrofuran / 20 °C
2.2: copper(I) iodide / tetrahydrofuran / 0 - 20 °C
3.1: sodium hydroxide / ethanol; H2O / 6.5 h / 20 °C
4.1: copper(I) oxide / acetonitrile / 0.5 h / Heating
View Scheme
参考文献
Chauder, Brian A.; Boros, Eric E.; Du, Kien S.; Kazmierski, Wieslaw M.; Koble, Cecilia S.; Thompson, James B.; Tabet, Elie A.
Synthetic Communications, 2006 , vol. 36, # 3 p. 279 - 284
