5-(Z-氨基)-1-戊醇合成路线 （共 12 条）
反应条件
1: Et3N / CH2Cl2 / 15 h / 20 °C
2: 79 percent / NaN3 / dimethylformamide / 24 h / 20 °C
3: 99 percent / H2 / Pd/C-ethylenediamine / tetrahydrofuran / 2 h / 20 °C / 760 Torr
View Scheme
参考文献
Hattori, Kazuyuki; Sajiki, Hironao; Hirota, Kosaku
Tetrahedron, 2000 , vol. 56, # 43 p. 8433 - 8441
反应条件
1: With oxalyl dichloride; dimethyl sulfoxide; triethylamine in dichloromethane
T=-78 - 0°C; Swern oxidation;
2: With hydrogenchloride in dichloromethane
T=20°C; 15 h; Further stages.;
参考文献
Okitsu; Suzuki; Kobayashi
Journal of Organic Chemistry, 2001 , vol. 66, # 3 p. 809 - 823
