5-[3,4-(亚甲基二氧基)苯基]-5-氧代戊酸合成路线 （共 7 条）
反应条件
potassium permanganate; Aliquatreg; 336 in water; benzene
T=0 - 45°C; Oxidation; 1.5 h;
参考文献
Gong, Young Dae; Tanaka, Hiroko; Iwasawa, Nobuharu; Narasaka, Koichi
Bulletin of the Chemical Society of Japan, 1998 , vol. 71, # 9 p. 2181 - 2185
反应条件
1.1: magnesium / diethyl ether
1.2: 74 percent / diethyl ether / 0 - 20 °C
2.1: 77 percent / chromium(VI) oxide; Celite / pyridine / 8 h / 20 °C
3.1: 73 percent / p-toluenesulfonic acid monohydrate; trimethyl orthoformate / 12 h / 20 °C
4.1: 82 percent / EtAlCl2 / CH2Cl2 / 1 h / -78 - 20 °C
5.1: 71 percent / methyltrioctylammonium chloride; KMnO4 / benzene; H2O / 1.5 h / 0 - 45 °C
View Scheme
参考文献
Gong, Young Dae; Tanaka, Hiroko; Iwasawa, Nobuharu; Narasaka, Koichi
Bulletin of the Chemical Society of Japan, 1998 , vol. 71, # 9 p. 2181 - 2185
反应条件
1: 73 percent / p-toluenesulfonic acid monohydrate; trimethyl orthoformate / 12 h / 20 °C
2: 82 percent / EtAlCl2 / CH2Cl2 / 1 h / -78 - 20 °C
3: 71 percent / methyltrioctylammonium chloride; KMnO4 / benzene; H2O / 1.5 h / 0 - 45 °C
View Scheme
参考文献
Gong, Young Dae; Tanaka, Hiroko; Iwasawa, Nobuharu; Narasaka, Koichi
Bulletin of the Chemical Society of Japan, 1998 , vol. 71, # 9 p. 2181 - 2185
反应条件
1: 77 percent / chromium(VI) oxide; Celite / pyridine / 8 h / 20 °C
2: 73 percent / p-toluenesulfonic acid monohydrate; trimethyl orthoformate / 12 h / 20 °C
3: 82 percent / EtAlCl2 / CH2Cl2 / 1 h / -78 - 20 °C
4: 71 percent / methyltrioctylammonium chloride; KMnO4 / benzene; H2O / 1.5 h / 0 - 45 °C
View Scheme
参考文献
Gong, Young Dae; Tanaka, Hiroko; Iwasawa, Nobuharu; Narasaka, Koichi
Bulletin of the Chemical Society of Japan, 1998 , vol. 71, # 9 p. 2181 - 2185
反应条件
1: 82 percent / EtAlCl2 / CH2Cl2 / 1 h / -78 - 20 °C
2: 71 percent / methyltrioctylammonium chloride; KMnO4 / benzene; H2O / 1.5 h / 0 - 45 °C
View Scheme
参考文献
Gong, Young Dae; Tanaka, Hiroko; Iwasawa, Nobuharu; Narasaka, Koichi
Bulletin of the Chemical Society of Japan, 1998 , vol. 71, # 9 p. 2181 - 2185
反应条件
aluminium trichloride
参考文献
Podda, G.; Maccioni, A.; Fadda, A.; Daolio, S.; Traldi, P.; Vecchi, E.
Organic Mass Spectrometry, 1983 , vol. 18, # 7 p. 318 - 320
反应条件
1: 67 percent / acetic anhydride / 8 h / Heating
2: 94 percent / DDQ / dioxane / 5 h / Heating
View Scheme
参考文献
Gong, Young Dae; Tanaka, Hiroko; Iwasawa, Nobuharu; Narasaka, Koichi
Bulletin of the Chemical Society of Japan, 1998 , vol. 71, # 9 p. 2181 - 2185
