2,4,6-三甲基苯胺合成路线 （共 254 条）
反应条件
potassium carbonate in acetonitrile
参考文献
Paczal, Attila; Benyei, Attila C.; Kotschy, Andras
Journal of Organic Chemistry, 2006 , vol. 71, # 16 p. 5969 - 5979
反应条件
1: With hydrogenchloride; water; sodium nitrite T=0°C; P=760.051 Torr; 1.5 h; 2: With sodium azide; sodium acetate in water T=0 - 20°C;
参考文献
Kloss, Florian; Koehn, Uwe; Jahn, Burkhard O.; Hager, Martin D.; Goerls, Helmar; Schubert, Ulrich S.
Chemistry - An Asian Journal, 2011 , vol. 6, # 10 p. 2816 - 2824
反应条件
1: water; chloroform 2: water; alcohol; ammonia View Scheme
参考文献
Eisenberg
Chemische Berichte, 1882 , vol. 15, p. 1018
反应条件
(i) HNO2, HBF4, (ii) (heating); Multistep reaction;
参考文献
Rhodia Limited
Patent: US6179970 B2, 2001 ;
反应条件
(i) NOCl, CHCl3, (ii) /BRN= 636559/, K2CO3; Multistep reaction;
参考文献
Robson,E. et al.
Journal of the Chemical Society [Section] C: Organic, 1968 , p. 1324 - 1328
参考文献
Angelino, S. A. G. F.; Buurman, D. J.; Plas, H. C. van der; Mueller, F.
Recueil: Journal of the Royal Netherlands Chemical Society, 1983 , vol. 102, # 6 p. 331 - 336
反应条件
sulfuric acid; sodium nitrite anschliessendes Erwaermen;
参考文献
Conroy, Firestone
Journal of the American Chemical Society, 1956 , vol. 78, p. 2290,2296
反应条件
tetrafluoroboric acid; N,N-dimethyl-formamide; sodium nitrite 1) water, 0 deg C, 2 h, 2) 60 deg C, 60 min; Yield given. Multistep reaction;
参考文献
Lahoti, R. J.; Parameswaran, V.; Wagle, D. R.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 9 p. 767 - 769
反应条件
1.1: potassium bis(trimethylsilyl)amide / tetrahydrofuran; toluene / 1.5 h / 0 - 20 °C 1.2: 62 percent / potassium bis(trimethylsilyl)amide / tetrahydrofuran; toluene / 0 - 20 °C 2.1: HNO3; H2SO4 3.1: ammonium formate / Pd/C / methanol View Scheme
参考文献
Wu, Chengde; Decker, E. Radford; Blok, Natalie; Bui, Huong; Chen, Qi; Raju; Bourgoyne, Andree R.; Knowles, Vippra; Biediger, Ronald J.; Market, Robert V.; Lin, Shuqun; Dupre, Brian; Kogan, Timothy P.; Holland, George W.; Brock, Tommy A.; Dixon, Richard A. F.
Journal of Medicinal Chemistry, 1999 , vol. 42, # 22 p. 4485 - 4499
反应条件
copper(l) iodide; potassium carbonate in N,N-dimethyl-formamide T=140°C; 0.166667 h; Microwave irradiation;
参考文献
Li, Zhenghua; Chen, Gang; Qiao, Shu; Liang, Ronghui; Lan, Cong; Xia, Zhining
Synthetic Communications, 2013 , vol. 43, # 9 p. 1270 - 1279
