2,4,6-三甲基苯胺合成路线 (共 254 条)
反应条件
n-ethyl morpholine; copper diacetate in N,N-dimethyl-formamide T=145°C; 3 h;
参考文献
Kaltenbronn; Scherrer; Short; Jones; Beatty; Saka; Winder; Wax; Williamson
Arzneimittel-Forschung/Drug Research, 1983 , vol. 33, # 4 A p. 621 - 627
参考文献
Badger,G.M. et al.
Australian Journal of Chemistry, 1964 , vol. 17, p. 1036 - 1049
反应条件
in toluene T=120°C; 24 h;
参考文献
Yang, Dan; Chen, Ying-Chun; Zhu, Nian-Yong
Organic Letters, 2004 , vol. 6, # 10 p. 1577 - 1580
反应条件
triethylamine in water T=20 - 90°C; 15 h;
参考文献
Findlater, Michael; Hill, Nicholas J.; Cowley, Alan H.
Dalton Transactions, 2008 , # 33 p. 4419 - 4423
反应条件
1: 75 percent / CH2Cl2 / 10 h / 40 °C 2: 91 percent / toluene / 24 h / 120 °C View Scheme
参考文献
Eisenberg
Chemische Berichte, 1882 , vol. 15, p. 1018
参考文献
Dyson; George
Journal of the Chemical Society, 1924 , vol. 125, p. 1704
反应条件
formic acid in ethanol T=70°C;
参考文献
Small, Brooke L.; Rios, Ray; Fernandez, Eric R.; Gerlach, Deidra L.; Halfen, Jason A.; Carney, Michael J.
Organometallics, 2010 , vol. 29, # 24 p. 6723 - 6731
反应条件
1: 89 percent / H2O; propan-2-ol / 24 h / 20 °C 2: 93 percent / NaBH4; HCl / tetrahydrofuran / 1.33 h / 0 - 20 °C View Scheme
参考文献
Arduengo III, Anthony J.; Krafczyk, Roland; Schmutzler, Reinhard; Craig, Hugh A.; Goerlich, Jens R.; Marshall, William J.; Unverzagt, Markus
Tetrahedron, 1999 , vol. 55, # 51 p. 14523 - 14534
参考文献
Prevost et al.
Bulletin de la Societe Chimique de France, 1953 , p. 78,81
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 17 p. 2235 - 2239