反应条件
1: SOCl2 / 2 h / Heating
2: 2 h / Heating
3: 1.) LDA / 1.) THF, n-heptane, -78 deg C, 0.5 h, 2.) THF, n-heptane, a) -78 deg C, 0.5 h, b) from -78 deg C to RT, 2 h, c) RT, overnight
4: 1.) LDA / 1.) THF, -78 deg C, 0.5 h, 2.) THF, a) -78 deg C, 0.5 h, b) from -78 deg C to RT, 2 h, c) RT, 13 h
5: NH2OH*HCl, aq. NaOH / ethanol / 1.5 h / Heating
View Scheme
参考文献
Rouchaud, J.; Gustin, F.; Moulard, C.
Bulletin des Societes Chimiques Belges, 1993 , vol. 102, # 8 p. 545 - 556
