N,N-二乙基氯甲酰胺合成路线 （共 193 条）
反应条件
Yield given. Multistep reaction;
参考文献
Hiiro, Tomoki; Mogami, Toshiaki; Kambe, Nobuaki; Fujiwara, Shin-Ichi; Sonoda, Noboru
Synthetic Communications, 1990 , vol. 20, # 5 p. 703 - 711
反应条件
aluminium trichloride
T=175 - 180°C; 3 h; changing amount of catalyst, temperature, and time; Product distribution;
参考文献
Isakova, A. P.; Naumov, Yu. A.; Nikeryasova, S. V.; Stepanova, A. A.
Journal of Organic Chemistry USSR (English Translation), 1982 , vol. 18, # 6 p. 1115 - 1119
Zhurnal Organicheskoi Khimii, 1982 , vol. 18, # 6 p. 1287 - 1291
反应条件
1: 91.6 percent / KHCO3 / acetone / 48 h / 20 - 30 °C
2: 93.4 percent / AlCl3 / nitrobenzene / 4.5 h / 25 - 30 °C
View Scheme
参考文献
Zoelss, G.
Arzneimittel Forschung, 1983 , vol. 33, # 1a p. 2 - 4
反应条件
in dichloromethane
T=20°C; 3 h;
参考文献
Khattab, Sherine Nabil; Hassan, Seham Yassin; Hamed, Ezzat Awad; Albericio, Fernando; Ayman, El-Faham
Bulletin of the Korean Chemical Society, 2010 , vol. 31, # 1 p. 75 - 81
反应条件
sodium azide in acetone
参考文献
Lwowski,W. et al.
Journal of Organic Chemistry, 1975 , vol. 40, p. 2608 - 2612
反应条件
1: n-butyllithium With CuCN in tetrahydrofuran
T=-30°C; 0.5 h;
2: N,N-diethyl carbamoyl chloride in tetrahydrofuran
T=-30 - 0°C; 2 h;
参考文献
Lemoucheux, Laurent; Seitz, Thomas; Rouden, Jacques; Lasne, Marie-Claire
Organic Letters, 2004 , vol. 6, # 21 p. 3703 - 3706
反应条件
1: 0.08 h / Heating
2: 72 percent / NiCl2(PPh3)2 / tetrahydrofuran / 2 h / 20 °C
View Scheme
参考文献
Lemoucheux; Rouden; Lasne
Tetrahedron Letters, 2000 , vol. 41, # 51 p. 9997 - 10001
参考文献
Ozaki; Nagoya
Bulletin of the Chemical Society of Japan, 1957 , vol. 30, p. 444,448
反应条件
pyridine in dichloromethane
T=0°C; 18 h;
参考文献
McBurney, Roy T.; Walton, John C.
Journal of the American Chemical Society, 2013 , vol. 135, # 19 p. 7349 - 7354
反应条件
n-butyllithium
1) hexane, Et2O, 30 min, -70 deg C, 2) Et2O, a) -70 deg C, 30 min, b) to -40 deg C, 30 min; Yield given. Multistep reaction;
参考文献
Berg, Keimpe J. van den; Leusen, Albert M. van
Recueil des Travaux Chimiques des Pays-Bas, 1993 , vol. 112, # 1 p. 7 - 14
